Helicobacter pylori CagA Causes Mitotic Impairment and Induces Chromosomal Instability

Infection with cagA-positive Helicobacter pylori is the strongest risk factor for the development of gastric carcinoma. The cagA gene product CagA, which is delivered into gastric epithelial cells, specifically binds to and aberrantly activates SHP-2 oncoprotein. CagA also interacts with and inhibit...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Umeda, Mayumi, Murata-Kamiya, Naoko, Saito, Yasuhiro, Ohba, Yusuke, Takahashi, Masayuki, Hatakeyama, Masanori
Formatua: Artikulua
Hizkuntza:English
Argitaratua: American Society for Biochemistry and Molecular Biology 2009
Gaiak:
Mechanisms of Signal Transduction
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755941/
https://ncbi.nlm.nih.gov/pubmed/19546211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035766
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC2755941/
https://ncbi.nlm.nih.gov/pubmed/19546211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.035766

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