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Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

Leptin is an adipocyte-derived cytokine that regulates food intake and body weight via interaction with its Ob receptor (ObR). Serum leptin levels are chronically elevated in obese humans, suggesting that obesity may be associated with leptin resistance and the inability to generate an adequate ObR...

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Autores principales: Carpenter, Laura Rocco, Farruggella, Thomas J., Symes, Aviva, Karow, Margaret L., Yancopoulos, George D., Stahl, Neil
Formato: Artículo
Lenguaje:en
Publicado: The National Academy of Sciences 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC27585/
https://ncbi.nlm.nih.gov/pubmed/9600917
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