Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.

We have isolated a murine homeobox-containing gene, Hox-5.1, by virtue of its relatedness to the Hox-1.4 gene. In situ hybridization to metaphase spreads mapped Hox-5.1 to band D of mouse chromosome 2. Sequence comparisons indicate that Hox-5.1 is the murine homolog of the human C13 homeobox-contain...

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Κύριοι συγγραφείς: Featherstone, M S, Baron, A, Gaunt, S J, Mattei, M G, Duboule, D
Μορφή: Άρθρο
Γλώσσα:en
Έκδοση: 1988
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Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC280515/
https://ncbi.nlm.nih.gov/pubmed/2898782
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spelling pubmed-2805152004-02-02 Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2. Featherstone, M S Baron, A Gaunt, S J Mattei, M G Duboule, D Proc Natl Acad Sci U S A Research Article We have isolated a murine homeobox-containing gene, Hox-5.1, by virtue of its relatedness to the Hox-1.4 gene. In situ hybridization to metaphase spreads mapped Hox-5.1 to band D of mouse chromosome 2. Sequence comparisons indicate that Hox-5.1 is the murine homolog of the human C13 homeobox-containing gene. Hox-5.1 also bears significant similarity to the Xenopus Xhox-1A homeobox-containing gene and the Drosophila deformed homeotic gene at N-terminal and homeobox regions. Hox-5.1 transcripts were detected in mouse embryos, in adult mouse testis, kidney, heart, and intestine, and in mouse embryonal carcinoma cells treated with retinoic acid. In situ hybridization to sections from whole mouse embryos revealed Hox-5.1 expression in spinal cord and prevertebrae. 1988-07 /pmc/articles/PMC280515/ /pubmed/2898782 Text en
institution US National Library of Medicine
collection PubMed Central
language en
format Article
topic Research Article
spellingShingle Research Article
Featherstone, M S
Baron, A
Gaunt, S J
Mattei, M G
Duboule, D
Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.
description We have isolated a murine homeobox-containing gene, Hox-5.1, by virtue of its relatedness to the Hox-1.4 gene. In situ hybridization to metaphase spreads mapped Hox-5.1 to band D of mouse chromosome 2. Sequence comparisons indicate that Hox-5.1 is the murine homolog of the human C13 homeobox-containing gene. Hox-5.1 also bears significant similarity to the Xenopus Xhox-1A homeobox-containing gene and the Drosophila deformed homeotic gene at N-terminal and homeobox regions. Hox-5.1 transcripts were detected in mouse embryos, in adult mouse testis, kidney, heart, and intestine, and in mouse embryonal carcinoma cells treated with retinoic acid. In situ hybridization to sections from whole mouse embryos revealed Hox-5.1 expression in spinal cord and prevertebrae.
author Featherstone, M S
Baron, A
Gaunt, S J
Mattei, M G
Duboule, D
author_facet Featherstone, M S
Baron, A
Gaunt, S J
Mattei, M G
Duboule, D
author_sort Featherstone, M S
title Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.
title_short Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.
title_full Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.
title_fullStr Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.
title_full_unstemmed Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.
title_sort hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2.
publishDate 1988
url https://ncbi.nlm.nih.gov/pmc/articles/PMC280515/
https://ncbi.nlm.nih.gov/pubmed/2898782
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