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Ligand-induced desensitization of B-cell membrane immunoglobulin-mediated Ca2+ mobilization and protein kinase C translocation.

Binding of ligand to B-cell membrane immunoglobulin (mIg) can lead to activation of a number of distinct biologic responses, including altered expression of genes encoding c-fos, c-myc, and Ia, as well as proliferation and immunologic tolerance. Tolerance could reflect a functional uncoupling of rec...

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Autors principals: Cambier, J, Chen, Z Z, Pasternak, J, Ransom, J, Sandoval, V, Pickles, H
Format: Article
Idioma:en
Publicat: 1988
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC281999/
https://ncbi.nlm.nih.gov/pubmed/3045817
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