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Heterotrimeric G-Proteins Interact Directly with Cytoskeletal Components to Modify Microtubule-Dependent Cellular Processes
A large percentage of current drugs target G-protein-coupled receptors, which couple to well-known signaling pathways involving cAMP or calcium. G-proteins themselves may subserve a second messenger function. Here, we review the role of tubulin and microtubules in directly mediating effects of heter...
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| Format: | Article |
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| Idioma: | en |
| Publicat: |
S. Karger AG
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836952/ https://ncbi.nlm.nih.gov/pubmed/19212143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000186693 |
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