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Coclustering of ErbB1 and ErbB2 Revealed by FRET-Sensitized Acceptor Bleaching

Classical theory states that ligand binding induces the dimerization of ErbB proteins, leading to their activation. Although we and other investigators have shown the existence of preformed homoclusters of ErbB receptors and analyzed their composition, the stoichiometry of their heteroclusters has n...

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Médium: Článek
Jazyk:en
Vydáno: The Biophysical Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895398/
https://ncbi.nlm.nih.gov/pubmed/20655838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.061
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