Effect of hydrochlorothiazide on the pharmacokinetics and pharmacodynamics of febuxostat, a non-purine selective inhibitor of xanthine oxidase

AIM: This study examined the effect of co-administration of febuxostat, an investigational urate lowering therapy, and hydrochlorothiazide on the pharmacokinetics and pharmacodynamics of febuxostat. METHODS: Healthy subjects (36 healthy men and women) received single doses of febuxostat 80 mg alone...

Full description

Saved in:
Bibliographic Details
Format: Article
Language:en
Published: Blackwell Science Inc 2010
Subjects:
Pharmacokinetic Dynamic Relationships
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909808/
https://ncbi.nlm.nih.gov/pubmed/20642548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03667.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC2909808/
https://ncbi.nlm.nih.gov/pubmed/20642548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03667.x

Similar Items