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STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western hemisphere, but its pathogenesis is still poorly understood. Constitutive tyrosine phosphorylation (p) of signal transducer and activator of transcription (STAT) 3 occurs in several solid tumors and hematologic malignancie...
Збережено в:
| Формат: | Стаття |
|---|---|
| Мова: | en |
| Опубліковано: |
American Society of Hematology
2010
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2918366/ https://ncbi.nlm.nih.gov/pubmed/20154216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-230060 |
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