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β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
The two widely coexpressed isoforms of β-arrestin (termed βarrestin 1 and 2) are highly similar in amino acid sequence. The β-arrestins bind phosphorylated heptahelical receptors to desensitize and target them to clathrin-coated pits for endocytosis. To better define differences in the roles of β-ar...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | en |
| Published: |
The National Academy of Sciences
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC29303/ https://ncbi.nlm.nih.gov/pubmed/11171997 |
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