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A shark antibody heavy chain encoded by a nonsomatically rearranged VDJ is preferentially expressed in early development and is convergent with mammalian IgG

In most vertebrate embryos and neonates studied to date unique antigen receptors (antibodies and T cell receptors) are expressed that possess a limited immune repertoire. We have isolated a subclass of IgM, IgM(1gj), from the nurse shark Ginglymostoma cirratum that is preferentially expressed in neo...

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Detalhes bibliográficos
Main Authors:	Rumfelt, Lynn L., Avila, David, Diaz, Marilyn, Bartl, Simona, McKinney, E. Churchill, Flajnik, Martin F., Addo, Marylyn M., Altfeld, Marcus, Rosenberg, Eric S., Eldridge, Robert L., Philips, Mary N., Habeeb, Kathleen, Khatri, Ashok, Brander, Christian, Robbins, Gregory K., Mazzara, Gail P., Goulder, Philip J. R., Walker, Bruce D., Morel, Laurence, Blenman, Kim R., Croker, Byron P., Wakeland, Edward K., Williamson, R. Anthony, Burgoon, Mark P., Owens, Gregory P., Ghausi, Omar, Leclerc, Estelle, Firme, Louise, Carlson, Sharon, Corboy, John, Parren, Paul W. H. I., Sanna, Pietro P., Gilden, Donald H., Burton, Dennis R., Karpas, Abraham, Dremucheva, Alla, Czepulkowski, Barbara H., Pain, Arnab, Ferguson, David J. P., Kai, Oscar, Urban, Britta C., Lowe, Brett, Marsh, Kevin, Roberts, David J., Holbert, Sébastien, Denghien, Isabelle, Kiechle, Tamara, Rosenblatt, Adam, Wellington, Cheryll, Hayden, Michael R., Margolis, Russell L., Ross, Christopher A., Dausset, Jean, Ferrante, Robert J., Néri, Christian, Ratovitski, Edward A., Patturajan, Meera, Hibi, Kenji, Trink, Barry, Yamaguchi, Kengo, Sidransky, David, Ramakrishnan, Vanitha, DeGuzman, Francis, Bao, Ming, Hall, Scott W., Leung, Lawrence L., Phillips, David R., Kovacs, Magdolna, Schally, Andrew V., Csernus, Balazs, Rekasi, Zoltan, Sieving, Paul A., Chaudhry, Prem, Kondo, Mineo, Provenzano, Matthew, Wu, David, Carlson, Thomas J., Bush, Ronald A., Thompson, Debra A., Tang, Hong, McLachlan, Alan, Ikuta, Tohru, Ausenda, Sabrina, Cappellini, Maria D., Felding-Habermann, Brunhilde, O'Toole, Timothy E., Smith, Jeffrey W., Fransvea, Emilia, Ruggeri, Zaverio M., Ginsberg, Mark H., Hughes, Paul E., Pampori, Nisar, Shattil, Sanford J., Saven, Alan, Mueller, Barbara M., Ruland, Jürgen, Sirard, Christian, Elia, Andrew, MacPherson, David, Wakeham, Andrew, Li, Limin, Luis de la Pompa, José, Cohen, Stanley N., Mak, Tak W., Hung, Siu Chun, Kang, Myung-Soo, Kieff, Elliott, Kunik, Talya, Tzfira, Tzvi, Kapulnik, Yoram, Gafni, Yedidya, Dingwall, Colin, Citovsky, Vitaly, Kawaguchi, Yasushi, Tanaka, Michiko, Yokoymama, Akihiko, Matsuda, Go, Kato, Kentaro, Kagawa, Hiroyuki, Hirai, Kanji, Roizman, Bernard, Dale, Colin, Young, Simon A., Haydon, Daniel T., Welburn, Susan C., Tijms, Marieke A., van Dinten, Leonie C., Gorbalenya, Alexander E., Snijder, Eric J., Wolf, Dana G., Courcelle, Charmain Tan, Prichard, Mark N., Mocarski, Edward S., Mazars, Edith, Lesjean, Sarah, Banuls, Anne-Laure, Gilbert, Michèle, Vincent, Véronique, Gicquel, Brigitte, Tibayrenc, Michel, Locht, Camille, Supply, Philip, Lee, Tai Sing, Nguyen, My, Santarelli, Luca, Gobbi, Gabriella, Debs, Pierre C., Sibille, Etienne L., Blier, Pierre, Hen, René, Heath, Mark J. S., Parkkila, Seppo, Parkkila, Anna-Kaisa, Rajaniemi, Hannu, Shah, Gul N., Grubb, Jeffrey H., Waheed, Abdul, Sly, William S., Timofeev, Igor, Grenier, François, Steriade, Mircea, Jiang, Cecilia H., Tsien, Joe Z., Schultz, Peter G., Hu, Yinghe, Sigman, Mariano, Cecchi, Guillermo A., Gilbert, Charles D., Magnasco, Marcelo O., Conner, J. M., Darracq, M. A., Roberts, Jeff, Tuszynski, M. H., Martínez-Torres, Ataúlfo, Miledi, Ricardo, Dubal, Dena B., Zhu, Hong, Yu, Jin, Rau, Shane W., Shughrue, Paul J., Merchenthaler, Istvan, Kindy, Mark S., Wise, Phyllis M., Ragnauth, A., Schuller, A., Morgan, M., Chan, J., Ogawa, S., Pintar, J., Bodnar, R. J., Pfaff, D. W., Khan, Zafar U., Koulen, Peter, Rubinstein, Marcelo, Grandy, David K., Goldman-Rakic, Patricia S., Chen, Jiang-Fan, Moratalla, Rosario, Impagnatiello, Francesco, Cuellar, Beatriz, Beilstein, Mark A., Hackett, Elizabeth, Fink, J. Stephen, Low, Malcolm J., Ongini, Ennio, Schwarzschild, Michael A., Ciccocioppo, Roberto, Sanna, Pietro Paolo, Weiss, Friedbert, Zhuang, Xiaoxi, Oosting, Ronald S., Jones, Sara R., Gainetdinov, Raul R., Miller, Gary W., Caron, Marc G., Carrera, M. Rocío A., Ashley, Jon A., Wirsching, Peter, Koob, George F., Janda, Kim D., Gracey, Andrew Y., Troll, Joshua V., Somero, George N., Kültz, Dietmar, Chakravarty, Devulapalli, Fruebis, Joachim, Tsao, Tsu-Shuen, Javorschi, Sandrine, Ebbets-Reed, Dana, Erickson, Mary Ruth S., Yen, Frances T., Bihain, Bernard E., Lodish, Harvey F., Wang, Renxue, Salem, Myriam, Yousef, Ibrahim M., Tuchweber, Beatriz, Lam, Ping, Childs, Sarah J., Helgason, Cheryl D., Ackerley, Cameron, Phillips, M. James, Ling, Victor, Ohno, Kinji, Tsujino, Akira, Brengman, Joan M., Harper, C. Michel, Bajzer, Zeljko, Udd, Bjarne, Beyring, Roger, Robb, Stephanie, Kirkham, Fenella J., Engel, Andrew G., Woo, Sun-Hee, Morad, Martin, Brannan, Stephen, Liotti, Mario, Egan, Gary, Shade, Robert, Madden, Lisa, Robillard, Rachel, Abplanalp, Bart, Stofer, Katie, Denton, Derek, Fox, Peter T., Lancaster, Jack, Zamarripa, Frank E., Parsons, Lawrence M., Robillard, Rachael, Oswald, Oliver, Martin, Thomas, Dominy, Peter J., Graham, Ian A., Mochizuki, Nobuyoshi, Brusslan, Judy A., Larkin, Robert, Nagatani, Akira, Chory, Joanne, Riely, Brendan K., Martin, Gregory B., Helliwell, Chris A., Chandler, Peter M., Poole, Andrew, Dennis, Elizabeth S., Peacock, W. James
Formato:	Artigo
Idioma:	English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English
Publicado em:	The National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.gov/pmc/articles/PMC29333/ https://ncbi.nlm.nih.gov/pubmed/11172027 https://ncbi.nlm.nih.gov/pmc/articles/PMC29334/ https://ncbi.nlm.nih.gov/pubmed/11172028 https://ncbi.nlm.nih.gov/pmc/articles/PMC29335/ https://ncbi.nlm.nih.gov/pubmed/11172029 https://ncbi.nlm.nih.gov/pmc/articles/PMC29336/ https://ncbi.nlm.nih.gov/pubmed/11172030 https://ncbi.nlm.nih.gov/pmc/articles/PMC29337/ https://ncbi.nlm.nih.gov/pubmed/11172031 https://ncbi.nlm.nih.gov/pmc/articles/PMC29338/ https://ncbi.nlm.nih.gov/pubmed/11172032 https://ncbi.nlm.nih.gov/pmc/articles/PMC29339/ https://ncbi.nlm.nih.gov/pubmed/11172033 https://ncbi.nlm.nih.gov/pmc/articles/PMC29340/ https://ncbi.nlm.nih.gov/pubmed/11172034 https://ncbi.nlm.nih.gov/pmc/articles/PMC29341/ https://ncbi.nlm.nih.gov/pubmed/11172035 https://ncbi.nlm.nih.gov/pmc/articles/PMC29342/ https://ncbi.nlm.nih.gov/pubmed/11172036 https://ncbi.nlm.nih.gov/pmc/articles/PMC29343/ https://ncbi.nlm.nih.gov/pubmed/11172037 https://ncbi.nlm.nih.gov/pmc/articles/PMC29344/ https://ncbi.nlm.nih.gov/pubmed/11172038 https://ncbi.nlm.nih.gov/pmc/articles/PMC29345/ https://ncbi.nlm.nih.gov/pubmed/11172039 https://ncbi.nlm.nih.gov/pmc/articles/PMC29346/ https://ncbi.nlm.nih.gov/pubmed/11172040 https://ncbi.nlm.nih.gov/pmc/articles/PMC29347/ https://ncbi.nlm.nih.gov/pubmed/11172041 https://ncbi.nlm.nih.gov/pmc/articles/PMC29348/ https://ncbi.nlm.nih.gov/pubmed/11172042 https://ncbi.nlm.nih.gov/pmc/articles/PMC29349/ https://ncbi.nlm.nih.gov/pubmed/11172043 https://ncbi.nlm.nih.gov/pmc/articles/PMC29350/ https://ncbi.nlm.nih.gov/pubmed/11172044 https://ncbi.nlm.nih.gov/pmc/articles/PMC29351/ https://ncbi.nlm.nih.gov/pubmed/11172045 https://ncbi.nlm.nih.gov/pmc/articles/PMC29352/ https://ncbi.nlm.nih.gov/pubmed/11172046 https://ncbi.nlm.nih.gov/pmc/articles/PMC29353/ https://ncbi.nlm.nih.gov/pubmed/11172047 https://ncbi.nlm.nih.gov/pmc/articles/PMC29354/ https://ncbi.nlm.nih.gov/pubmed/11172048 https://ncbi.nlm.nih.gov/pmc/articles/PMC29355/ https://ncbi.nlm.nih.gov/pubmed/11172049 https://ncbi.nlm.nih.gov/pmc/articles/PMC29356/ https://ncbi.nlm.nih.gov/pubmed/11172050 https://ncbi.nlm.nih.gov/pmc/articles/PMC29357/ https://ncbi.nlm.nih.gov/pubmed/11172051 https://ncbi.nlm.nih.gov/pmc/articles/PMC29358/ https://ncbi.nlm.nih.gov/pubmed/11172052 https://ncbi.nlm.nih.gov/pmc/articles/PMC29359/ https://ncbi.nlm.nih.gov/pubmed/11172053 https://ncbi.nlm.nih.gov/pmc/articles/PMC29360/ https://ncbi.nlm.nih.gov/pubmed/11172054 https://ncbi.nlm.nih.gov/pmc/articles/PMC29361/ https://ncbi.nlm.nih.gov/pubmed/11172055 https://ncbi.nlm.nih.gov/pmc/articles/PMC29362/ https://ncbi.nlm.nih.gov/pubmed/11172056 https://ncbi.nlm.nih.gov/pmc/articles/PMC29363/ https://ncbi.nlm.nih.gov/pubmed/11172057 https://ncbi.nlm.nih.gov/pmc/articles/PMC29364/ https://ncbi.nlm.nih.gov/pubmed/11172058 https://ncbi.nlm.nih.gov/pmc/articles/PMC29365/ https://ncbi.nlm.nih.gov/pubmed/11172059 https://ncbi.nlm.nih.gov/pmc/articles/PMC29366/ https://ncbi.nlm.nih.gov/pubmed/11172060 https://ncbi.nlm.nih.gov/pmc/articles/PMC29367/ https://ncbi.nlm.nih.gov/pubmed/11172061 https://ncbi.nlm.nih.gov/pmc/articles/PMC29368/ https://ncbi.nlm.nih.gov/pubmed/11172062 https://ncbi.nlm.nih.gov/pmc/articles/PMC29369/ https://ncbi.nlm.nih.gov/pubmed/11172063 https://ncbi.nlm.nih.gov/pmc/articles/PMC29370/ https://ncbi.nlm.nih.gov/pubmed/11172064 https://ncbi.nlm.nih.gov/pmc/articles/PMC29371/ https://ncbi.nlm.nih.gov/pubmed/11172065 https://ncbi.nlm.nih.gov/pmc/articles/PMC29372/ https://ncbi.nlm.nih.gov/pubmed/11172066 https://ncbi.nlm.nih.gov/pmc/articles/PMC29373/ https://ncbi.nlm.nih.gov/pubmed/11172067 https://ncbi.nlm.nih.gov/pmc/articles/PMC29374/ https://ncbi.nlm.nih.gov/pubmed/11172068 https://ncbi.nlm.nih.gov/pmc/articles/PMC29375/ https://ncbi.nlm.nih.gov/pubmed/11172069 https://ncbi.nlm.nih.gov/pmc/articles/PMC29376/ https://ncbi.nlm.nih.gov/pubmed/11172070 https://ncbi.nlm.nih.gov/pmc/articles/PMC29377/ https://ncbi.nlm.nih.gov/pubmed/11172071 https://ncbi.nlm.nih.gov/pmc/articles/PMC29378/ https://ncbi.nlm.nih.gov/pubmed/11172072 https://ncbi.nlm.nih.gov/pmc/articles/PMC29379/ https://ncbi.nlm.nih.gov/pubmed/11172073 https://ncbi.nlm.nih.gov/pmc/articles/PMC29380/ https://ncbi.nlm.nih.gov/pubmed/11172074 https://ncbi.nlm.nih.gov/pmc/articles/PMC29381/ https://ncbi.nlm.nih.gov/pubmed/11172075 https://ncbi.nlm.nih.gov/pmc/articles/PMC29382/ https://ncbi.nlm.nih.gov/pubmed/11172076
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A shark antibody heavy chain encoded by a nonsomatically rearranged VDJ is preferentially expressed in early development and is convergent with mammalian IgG

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