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c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication.
Replicating activity of SV40 origin-containing plasmid was tested in human cells as well as in monkey CosI cells. All the plasmids possessing SV40 ori sequences could replicate, even in the absence of SV40 T antigen, in human HL-60 and Raji cells which are expressing c-myc gene at high level. The co...
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pubmed-305925 |
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pubmed-3059252004-02-25 c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication. Iguchi-Ariga, S M Itani, T Yamaguchi, M Ariga, H Nucleic Acids Res Replicating activity of SV40 origin-containing plasmid was tested in human cells as well as in monkey CosI cells. All the plasmids possessing SV40 ori sequences could replicate, even in the absence of SV40 T antigen, in human HL-60 and Raji cells which are expressing c-myc gene at high level. The copy numbers of the replicated plasmids in these human cells were 1/100 as high as in monkey CosI cells which express SV40 T antigen constitutively. Exactly the same plasmids as the transfected original ones were recovered from the Hirt supernatant of the transfected HL-60 cells. Furthermore, replication of the SV40 ori-containing plasmids in HL-60 cells was inhibited by anti-c-myc antibody co-transfected into the cells. These results indicate that the c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication. 1987-06-25 /pmc/articles/PMC305925/ /pubmed/3037484 Text en |
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US National Library of Medicine |
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PubMed Central |
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English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English English |
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Article |
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Replicating activity of SV40 origin-containing plasmid was tested in human cells as well as in monkey CosI cells. All the plasmids possessing SV40 ori sequences could replicate, even in the absence of SV40 T antigen, in human HL-60 and Raji cells which are expressing c-myc gene at high level. The copy numbers of the replicated plasmids in these human cells were 1/100 as high as in monkey CosI cells which express SV40 T antigen constitutively. Exactly the same plasmids as the transfected original ones were recovered from the Hirt supernatant of the transfected HL-60 cells. Furthermore, replication of the SV40 ori-containing plasmids in HL-60 cells was inhibited by anti-c-myc antibody co-transfected into the cells. These results indicate that the c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication. |
| author |
Iguchi-Ariga, S M Itani, T Yamaguchi, M Ariga, H de Wind, N Parren, P Stuitje, A R Meijer, M Bower, M Summers, M F Powell, C Shinozuka, K Regan, J B Zon, G Wilson, W D Geisen, R M Fatscher, H P Fuchs, E Hinrichs, W Steifa, M Saenger, W Eckstein, F Yeung, A T Jones, B K Capraro, M Chu, T Tung, C S Harvey, S C Hong, H J Yoo, S H Yoo, O J Imai, R Sekiguchi, T Nosoh, Y Tsuda, K Seidel, U Bober, E Winter, B Lenz, S Lohse, P Arnold, H H Lalanne, J L Lucero, M le Moullec, J M Smith, W J Tunnacliffe, A Rabbitts, T H Shimada, T McAlister-Henn, L Blaber, M Bradshaw, R A Nisco, S J Janson, L Bark, C Pettersson, U Johnston, L H White, J H Johnson, A L Lucchini, G Plevani, P Van Dyke, M W Roeder, R G Rostas, K Morton, S J Picksley, S M Lloyd, R G Lee, K L Pentecost, B T D'Anna, J A Tobey, R A Gurley, L R Dixon, G H Po, T Steger, G Rosenbaum, V Kaper, J Riesner, D Steger, G Po, T Kaper, J Riesner, D Esposito, F Sinden, R R Larsen, J E Albrechtsen, B Valentin-Hansen, P Makaroff, C A Palmer, J D Sands, J F Cummings, H S Sacerdot, C Dondon, L Grunberg-Manago, M Hershey, J W Poncz, M Sutton, M Delgrosso, K Schwartz, E Surrey, S Dworniczak, B Mirault, M E Paulson, K E Matera, A G Deka, N Schmid, C W Berends, T Gamble, P E Mullet, J E Shimamoto, N Ikushima, N Utiyama, H Tachibana, H Horie, K Leavitt, M C Ito, J Zhou, K Brisco, P R Hinkkanen, A E Kohlhaw, G B Li, P Medon, P P Skingle, D C Lanser, J A Symons, R H Hoffmann, P U McLaughlin, L W Zuckermann, R Corey, D Schultz, P Levinson, G Gutman, G A Klig, L S Crawford, I P Yanofsky, C Ghosh, S S Musso, G F Gingeras, T R Kwoh, D Y Davis, G R Koller, H T Frondorf, K A Maschner, P D Vaughn, J C Chapman, K A Burgess, R R Poljak, L G Gralla, J D Saez, L J Gianola, K M McNally, E M Feghali, R Eddy, R Shows, T B Leinwand, L A Andrews, G K Adamson, E D Stange, N Gross, H J Beier, H Wilhelm, M L Wilhelm, F X Hall, R M Ksenzenko, V N Shlyapnikov, M G Azbarov, V G Garcia, O Kryukov, V M Bayev, A A Potter, S S Lloyd, J A Seto, N O Hayashi, S Tener, G M |
| spellingShingle |
Iguchi-Ariga, S M Itani, T Yamaguchi, M Ariga, H de Wind, N Parren, P Stuitje, A R Meijer, M Bower, M Summers, M F Powell, C Shinozuka, K Regan, J B Zon, G Wilson, W D Geisen, R M Fatscher, H P Fuchs, E Hinrichs, W Steifa, M Saenger, W Eckstein, F Yeung, A T Jones, B K Capraro, M Chu, T Tung, C S Harvey, S C Hong, H J Yoo, S H Yoo, O J Imai, R Sekiguchi, T Nosoh, Y Tsuda, K Seidel, U Bober, E Winter, B Lenz, S Lohse, P Arnold, H H Lalanne, J L Lucero, M le Moullec, J M Smith, W J Tunnacliffe, A Rabbitts, T H Shimada, T McAlister-Henn, L Blaber, M Bradshaw, R A Nisco, S J Janson, L Bark, C Pettersson, U Johnston, L H White, J H Johnson, A L Lucchini, G Plevani, P Van Dyke, M W Roeder, R G Rostas, K Morton, S J Picksley, S M Lloyd, R G Lee, K L Pentecost, B T D'Anna, J A Tobey, R A Gurley, L R Dixon, G H Po, T Steger, G Rosenbaum, V Kaper, J Riesner, D Steger, G Po, T Kaper, J Riesner, D Esposito, F Sinden, R R Larsen, J E Albrechtsen, B Valentin-Hansen, P Makaroff, C A Palmer, J D Sands, J F Cummings, H S Sacerdot, C Dondon, L Grunberg-Manago, M Hershey, J W Poncz, M Sutton, M Delgrosso, K Schwartz, E Surrey, S Dworniczak, B Mirault, M E Paulson, K E Matera, A G Deka, N Schmid, C W Berends, T Gamble, P E Mullet, J E Shimamoto, N Ikushima, N Utiyama, H Tachibana, H Horie, K Leavitt, M C Ito, J Zhou, K Brisco, P R Hinkkanen, A E Kohlhaw, G B Li, P Medon, P P Skingle, D C Lanser, J A Symons, R H Hoffmann, P U McLaughlin, L W Zuckermann, R Corey, D Schultz, P Levinson, G Gutman, G A Klig, L S Crawford, I P Yanofsky, C Ghosh, S S Musso, G F Gingeras, T R Kwoh, D Y Davis, G R Koller, H T Frondorf, K A Maschner, P D Vaughn, J C Chapman, K A Burgess, R R Poljak, L G Gralla, J D Saez, L J Gianola, K M McNally, E M Feghali, R Eddy, R Shows, T B Leinwand, L A Andrews, G K Adamson, E D Stange, N Gross, H J Beier, H Wilhelm, M L Wilhelm, F X Hall, R M Ksenzenko, V N Shlyapnikov, M G Azbarov, V G Garcia, O Kryukov, V M Bayev, A A Potter, S S Lloyd, J A Seto, N O Hayashi, S Tener, G M c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication. |
| author_facet |
Iguchi-Ariga, S M Itani, T Yamaguchi, M Ariga, H de Wind, N Parren, P Stuitje, A R Meijer, M Bower, M Summers, M F Powell, C Shinozuka, K Regan, J B Zon, G Wilson, W D Geisen, R M Fatscher, H P Fuchs, E Hinrichs, W Steifa, M Saenger, W Eckstein, F Yeung, A T Jones, B K Capraro, M Chu, T Tung, C S Harvey, S C Hong, H J Yoo, S H Yoo, O J Imai, R Sekiguchi, T Nosoh, Y Tsuda, K Seidel, U Bober, E Winter, B Lenz, S Lohse, P Arnold, H H Lalanne, J L Lucero, M le Moullec, J M Smith, W J Tunnacliffe, A Rabbitts, T H Shimada, T McAlister-Henn, L Blaber, M Bradshaw, R A Nisco, S J Janson, L Bark, C Pettersson, U Johnston, L H White, J H Johnson, A L Lucchini, G Plevani, P Van Dyke, M W Roeder, R G Rostas, K Morton, S J Picksley, S M Lloyd, R G Lee, K L Pentecost, B T D'Anna, J A Tobey, R A Gurley, L R Dixon, G H Po, T Steger, G Rosenbaum, V Kaper, J Riesner, D Steger, G Po, T Kaper, J Riesner, D Esposito, F Sinden, R R Larsen, J E Albrechtsen, B Valentin-Hansen, P Makaroff, C A Palmer, J D Sands, J F Cummings, H S Sacerdot, C Dondon, L Grunberg-Manago, M Hershey, J W Poncz, M Sutton, M Delgrosso, K Schwartz, E Surrey, S Dworniczak, B Mirault, M E Paulson, K E Matera, A G Deka, N Schmid, C W Berends, T Gamble, P E Mullet, J E Shimamoto, N Ikushima, N Utiyama, H Tachibana, H Horie, K Leavitt, M C Ito, J Zhou, K Brisco, P R Hinkkanen, A E Kohlhaw, G B Li, P Medon, P P Skingle, D C Lanser, J A Symons, R H Hoffmann, P U McLaughlin, L W Zuckermann, R Corey, D Schultz, P Levinson, G Gutman, G A Klig, L S Crawford, I P Yanofsky, C Ghosh, S S Musso, G F Gingeras, T R Kwoh, D Y Davis, G R Koller, H T Frondorf, K A Maschner, P D Vaughn, J C Chapman, K A Burgess, R R Poljak, L G Gralla, J D Saez, L J Gianola, K M McNally, E M Feghali, R Eddy, R Shows, T B Leinwand, L A Andrews, G K Adamson, E D Stange, N Gross, H J Beier, H Wilhelm, M L Wilhelm, F X Hall, R M Ksenzenko, V N Shlyapnikov, M G Azbarov, V G Garcia, O Kryukov, V M Bayev, A A Potter, S S Lloyd, J A Seto, N O Hayashi, S Tener, G M |
| author_sort |
Iguchi-Ariga, S M |
| title |
c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication. |
| title_short |
c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication. |
| title_full |
c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication. |
| title_fullStr |
c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication. |
| title_full_unstemmed |
c-myc protein can be substituted for SV40 T antigen in SV40 DNA replication. |
| title_sort |
c-myc protein can be substituted for sv40 t antigen in sv40 dna replication. |
| publishDate |
1987 |
| url |
https://ncbi.nlm.nih.gov/pmc/articles/PMC305925/ https://ncbi.nlm.nih.gov/pubmed/3037484 https://ncbi.nlm.nih.gov/pmc/articles/PMC305926/ https://ncbi.nlm.nih.gov/pubmed/3037485 https://ncbi.nlm.nih.gov/pmc/articles/PMC305927/ https://ncbi.nlm.nih.gov/pubmed/3601658 https://ncbi.nlm.nih.gov/pmc/articles/PMC305928/ https://ncbi.nlm.nih.gov/pubmed/3601659 https://ncbi.nlm.nih.gov/pmc/articles/PMC305929/ https://ncbi.nlm.nih.gov/pubmed/3601660 https://ncbi.nlm.nih.gov/pmc/articles/PMC305930/ https://ncbi.nlm.nih.gov/pubmed/3299260 https://ncbi.nlm.nih.gov/pmc/articles/PMC305931/ https://ncbi.nlm.nih.gov/pubmed/3299261 https://ncbi.nlm.nih.gov/pmc/articles/PMC305932/ https://ncbi.nlm.nih.gov/pubmed/3648680 https://ncbi.nlm.nih.gov/pmc/articles/PMC305933/ https://ncbi.nlm.nih.gov/pubmed/3110742 https://ncbi.nlm.nih.gov/pmc/articles/PMC305934/ https://ncbi.nlm.nih.gov/pubmed/3601661 https://ncbi.nlm.nih.gov/pmc/articles/PMC305935/ https://ncbi.nlm.nih.gov/pubmed/3601662 https://ncbi.nlm.nih.gov/pmc/articles/PMC305936/ https://ncbi.nlm.nih.gov/pubmed/2955286 https://ncbi.nlm.nih.gov/pmc/articles/PMC305937/ https://ncbi.nlm.nih.gov/pubmed/3601663 https://ncbi.nlm.nih.gov/pmc/articles/PMC305938/ https://ncbi.nlm.nih.gov/pubmed/3299262 https://ncbi.nlm.nih.gov/pmc/articles/PMC305943/ https://ncbi.nlm.nih.gov/pubmed/3601664 https://ncbi.nlm.nih.gov/pmc/articles/PMC305944/ https://ncbi.nlm.nih.gov/pubmed/3299263 https://ncbi.nlm.nih.gov/pmc/articles/PMC305945/ https://ncbi.nlm.nih.gov/pubmed/3601665 https://ncbi.nlm.nih.gov/pmc/articles/PMC305946/ https://ncbi.nlm.nih.gov/pubmed/3037486 https://ncbi.nlm.nih.gov/pmc/articles/PMC305947/ https://ncbi.nlm.nih.gov/pubmed/3601666 https://ncbi.nlm.nih.gov/pmc/articles/PMC305948/ https://ncbi.nlm.nih.gov/pubmed/3601667 https://ncbi.nlm.nih.gov/pmc/articles/PMC305949/ https://ncbi.nlm.nih.gov/pubmed/3601668 https://ncbi.nlm.nih.gov/pmc/articles/PMC305950/ https://ncbi.nlm.nih.gov/pubmed/3037487 https://ncbi.nlm.nih.gov/pmc/articles/PMC305951/ https://ncbi.nlm.nih.gov/pubmed/3299264 https://ncbi.nlm.nih.gov/pmc/articles/PMC305952/ https://ncbi.nlm.nih.gov/pubmed/3601669 https://ncbi.nlm.nih.gov/pmc/articles/PMC305953/ https://ncbi.nlm.nih.gov/pubmed/3037488 https://ncbi.nlm.nih.gov/pmc/articles/PMC305954/ https://ncbi.nlm.nih.gov/pubmed/3601670 https://ncbi.nlm.nih.gov/pmc/articles/PMC305955/ https://ncbi.nlm.nih.gov/pubmed/3037489 https://ncbi.nlm.nih.gov/pmc/articles/PMC305956/ https://ncbi.nlm.nih.gov/pubmed/3037490 https://ncbi.nlm.nih.gov/pmc/articles/PMC305957/ https://ncbi.nlm.nih.gov/pubmed/3601671 https://ncbi.nlm.nih.gov/pmc/articles/PMC305958/ https://ncbi.nlm.nih.gov/pubmed/3299265 https://ncbi.nlm.nih.gov/pmc/articles/PMC305959/ https://ncbi.nlm.nih.gov/pubmed/3601672 https://ncbi.nlm.nih.gov/pmc/articles/PMC305960/ https://ncbi.nlm.nih.gov/pubmed/3299266 https://ncbi.nlm.nih.gov/pmc/articles/PMC305961/ https://ncbi.nlm.nih.gov/pubmed/3299267 https://ncbi.nlm.nih.gov/pmc/articles/PMC305962/ https://ncbi.nlm.nih.gov/pubmed/3299268 https://ncbi.nlm.nih.gov/pmc/articles/PMC305963/ https://ncbi.nlm.nih.gov/pubmed/3601673 https://ncbi.nlm.nih.gov/pmc/articles/PMC305964/ https://ncbi.nlm.nih.gov/pubmed/3299269 https://ncbi.nlm.nih.gov/pmc/articles/PMC305965/ https://ncbi.nlm.nih.gov/pubmed/3299270 https://ncbi.nlm.nih.gov/pmc/articles/PMC305966/ https://ncbi.nlm.nih.gov/pubmed/3601674 https://ncbi.nlm.nih.gov/pmc/articles/PMC305967/ https://ncbi.nlm.nih.gov/pubmed/3601675 https://ncbi.nlm.nih.gov/pmc/articles/PMC305968/ https://ncbi.nlm.nih.gov/pubmed/3037491 https://ncbi.nlm.nih.gov/pmc/articles/PMC305969/ https://ncbi.nlm.nih.gov/pubmed/3299271 https://ncbi.nlm.nih.gov/pmc/articles/PMC305970/ https://ncbi.nlm.nih.gov/pubmed/3037492 https://ncbi.nlm.nih.gov/pmc/articles/PMC305971/ https://ncbi.nlm.nih.gov/pubmed/3037493 https://ncbi.nlm.nih.gov/pmc/articles/PMC305972/ https://ncbi.nlm.nih.gov/pubmed/3601676 https://ncbi.nlm.nih.gov/pmc/articles/PMC305973/ https://ncbi.nlm.nih.gov/pubmed/3648681 https://ncbi.nlm.nih.gov/pmc/articles/PMC305974/ https://ncbi.nlm.nih.gov/pubmed/3601677 https://ncbi.nlm.nih.gov/pmc/articles/PMC305975/ https://ncbi.nlm.nih.gov/pubmed/3037494 https://ncbi.nlm.nih.gov/pmc/articles/PMC305976/ https://ncbi.nlm.nih.gov/pubmed/3299272 https://ncbi.nlm.nih.gov/pmc/articles/PMC305977/ https://ncbi.nlm.nih.gov/pubmed/3037495 https://ncbi.nlm.nih.gov/pmc/articles/PMC305978/ https://ncbi.nlm.nih.gov/pubmed/3110743 |
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