Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling

Left ventricular remodeling that occurs after myocardial infarction (MI) and pressure overload is generally accepted as a determinant of the clinical course of heart failure. The molecular mechanism of this process, however, remains to be elucidated. Apoptosis signal-regulating kinase 1 (ASK1) is a...

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Bibliografiske detaljer
Main Authors: Yamaguchi, Osamu, Higuchi, Yoshiharu, Hirotani, Shinichi, Kashiwase, Kazunori, Nakayama, Hiroyuki, Hikoso, Shungo, Takeda, Toshihiro, Watanabe, Tetsuya, Asahi, Michio, Taniike, Masayuki, Matsumura, Yasushi, Tsujimoto, Ikuko, Hongo, Kenichi, Kusakari, Yoichiro, Kurihara, Satoshi, Nishida, Kazuhiko, Ichijo, Hidenori, Hori, Masatsugu, Otsu, Kinya
Format: Artigo
Sprog:en
Udgivet: National Academy of Sciences 2003
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC307662/
https://ncbi.nlm.nih.gov/pubmed/14665690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2136717100
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