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DNA unwinding by replication protein A is a property of the 70 kDa subunit and is facilitated by phosphorylation of the 32 kDa subunit.
Replication protein A (RP-A) is a heterotrimeric single-stranded DNA binding protein with important functions in DNA replication, DNA repair and DNA recombination. We have found that RP-A from calf thymus can unwind DNA in the absence of ATP and MgCl2, two essential cofactors for bona fide DNA helic...
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| Главные авторы: | , |
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| Формат: | Статья |
| Язык: | en |
| Опубликовано: |
1993
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC309862/ https://ncbi.nlm.nih.gov/pubmed/8396234 |
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