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Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway

Although hematopoietic stem cell transplantation and gene therapy have the potential to cure β-thalassemia and sickle cell disease, they are not currently available to most people with these diseases. In the near term, pharmacologic induction of fetal hemoglobin (HbF) may offer the best possibility...

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Sparad:
Bibliografiska uppgifter
Materialtyp: Artikel
Språk:en
Publicerad: American Society of Hematology 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112042/
https://ncbi.nlm.nih.gov/pubmed/21464371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-314096
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