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Echinomycin and distamycin induce rotation of nucleosome core DNA.
When nucleosome cores reconstituted from chicken erythrocyte histones and a 160 bp DNA molecule are exposed to echinomycin, a bis-intercalating antitumour antibiotic, the DNA appears to rotate with respect to the histone octamer by about half a turn. New bands appear in patterns of DNAase I digestio...
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| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Sprog: | en |
| Udgivet: |
1986
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC311699/ https://ncbi.nlm.nih.gov/pubmed/3763391 |
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