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High-Throughput MALDI-TOF Discovery of Genomic Sequence Polymorphisms
We describe a comparative sequencing strategy that is based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analyses of complete base-specific cleavage reactions of a target sequence. The target is converted to a DNA/RNA mosaic structure after PCR ampli...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | en |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC314289/ https://ncbi.nlm.nih.gov/pubmed/14707174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.1692304 |
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