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Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP

Ribonuclease P (RNase P) is a ribonucleoprotein enzyme that cleaves precursor tRNA transcripts to give mature 5′ ends. RNase P in eubacteria has a large, catalytic RNA subunit and a small protein subunit that are required for precursor tRNA cleavage in vivo. Although the eukaryotic holoenzymes have...

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Main Authors: Chamberlain, Joel R., Lee, Yoon, Lane, William S., Engelke, David R.
Formato: Artigo
Idioma:en
Publicado: Cold Spring Harbor Laboratory Press 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC316871/
https://ncbi.nlm.nih.gov/pubmed/9620854
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