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Vascular endothelial growth factor (VEGF) fails to improve blood flow and to promote collateralization in a diabetic mouse ischemic hindlimb model

BACKGROUND: Angiogenic therapy with vascular endothelial growth factor (VEGF) has been proposed as a treatment paradigm for patients suffering from an insufficiency of collateral vessels. Diabetes is associated with increase in the production of VEGF and therefore additional VEGF may not be benefici...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Roguin, Ariel, Nitecki, Samy, Rubinstein, Irit, Nevo, Eviatar, Avivi, Aaron, Levy, Nina S, Abassi, Zaid A, Sabo, Edmond, Lache, Orit, Frank, Meira, Hoffman, Aaron, Levy, Andrew P
Format: Artikel
Sprache:en
Veröffentlicht: BioMed Central 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC320491/
https://ncbi.nlm.nih.gov/pubmed/14683529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-2-18
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