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Formation of a stable complex between the human immunodeficiency virus integrase protein and viral DNA.

The integrase (IN) protein of the human immunodeficiency virus (HIV) mediates two distinct reactions: (i) specific removal of two nucleotides from the 3' ends of the viral DNA and (ii) integration of the viral DNA into target DNA. Although IN discriminates between specific (viral) DNA and nonsp...

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Bibliografiske detaljer
Main Authors: Vink, C, Lutzke, R A, Plasterk, R H
Format: Artigo
Sprog:en
Udgivet: 1994
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC331896/
https://ncbi.nlm.nih.gov/pubmed/7937134
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