Ezrin-Radixin-Moesin-binding Sequence of PSGL-1 Glycoprotein Regulates Leukocyte Rolling on Selectins and Activation of Extracellular Signal-regulated Kinases

P-selectin glycoprotein ligand-1 (PSGL-1) mediates the capture (tethering) of free-flowing leukocytes and subsequent rolling on selectins. PSGL-1 interactions with endothelial selectins activate Src kinases and spleen tyrosine kinase (Syk), leading to α(L)β(2) integrin-dependent leukocyte slow rolli...

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Format: Artigo
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Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322991/
https://ncbi.nlm.nih.gov/pubmed/22311979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.318022
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC3322991/
https://ncbi.nlm.nih.gov/pubmed/22311979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.318022

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