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Non–cell-autonomous hedgehog signaling promotes murine B lymphopoiesis from hematopoietic progenitors
The role of hedgehog (Hh) signaling in B lymphopoiesis has remained unclear. We observed that the proliferation of pro-B cells in stromal cocultures was impaired by interruption of Hh signaling, prompting us to investigate whether the target of Hh antagonism was intrinsic or extrinsic to the B-lymph...
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| フォーマット: | 論文 |
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| 言語: | en |
| 出版事項: |
American Society of Hematology
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369680/ https://ncbi.nlm.nih.gov/pubmed/22517907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-397976 |
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