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Rate of degradation of [alpha]- and [beta]-oligodeoxynucleotides in Xenopus oocytes. Implications for anti-messenger strategies.

End-labelled oligodeoxynucleotides were injected into Xenopus laevis oocytes and their degradation products were analysed by high-performance ion-exchange liquid chromatography after various times of incubation. The oligonucleotides were synthesised with either the natural [beta] anomers or the synt...

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Detalles Bibliográficos
Main Authors: Cazenave, C, Chevrier, M, Nguyen, T T, Hélène, C
Formato: Artigo
Idioma:en
Publicado: 1987
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC339959/
https://ncbi.nlm.nih.gov/pubmed/2447563
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