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A theory of allelic and isotypic exclusion for immunoglobulin genes.
Heavy (H) chain binding protein (BiP), which binds to free immunoglobulin H chain of the mu and gamma classes, can be demonstrated in pre-B-cells. It is proposed that the displacement of BiP from H chain by light (L) chain terminates the activity of the enzyme system, L-generase, which catalyzes DNA...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | en |
| Udgivet: |
1982
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC347257/ https://ncbi.nlm.nih.gov/pubmed/6817330 |
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