An anti-CD45RO immunotoxin kills HIV-latently infected cells from individuals on HAART with little effect on CD8 memory

CD4(+) CD45RO(+) T cells are the major latent viral reservoir in HIV-infected individuals and hence a major obstacle in curing the disease. An anti-CD45RO immunotoxin (IT) can decrease the number of both productively and latently infected CD4(+) T cells obtained from HIV-infected individuals with de...

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Autors principals: Saavedra-Lozano, J., Cao, Y., Callison, J., Sarode, R., Sodora, D., Edgar, J., Hatfield, J., Picker, L., Peterson, D., Ramilo, O., Vitetta, E. S.
Format: Article
Idioma:en
Publicat: National Academy of Sciences 2004
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC356978/
https://ncbi.nlm.nih.gov/pubmed/14983037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308381100
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https://ncbi.nlm.nih.gov/pmc/articles/PMC356978/
https://ncbi.nlm.nih.gov/pubmed/14983037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308381100

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