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Genes transferred by retroviral vectors into normal and mutant myoblasts in primary cultures are expressed in myotubes.

Retroviral vectors were used to transfer genes efficiently into rat and dog myoblasts in primary cultures under conditions which permitted the transduced myoblasts to differentiate into myotubes expressing the transferred genes. The transduced myotubes expressed normal markers of differentiation and...

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Bibliographic Details
Main Authors: Smith, B F, Hoffman, R K, Giger, U, Wolfe, J H
Format: Article
Language:en
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC360696/
https://ncbi.nlm.nih.gov/pubmed/2160598
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