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Alpha 2-adrenergic agonists stimulate DNA synthesis in Chinese hamster lung fibroblasts transfected with a human alpha 2-adrenergic receptor gene.

To test the hypothesis that agents activating receptors negatively coupled to adenylyl cyclase (AC) can stimulate cell proliferation, we have expressed a human alpha 2-adrenergic receptor (alpha 2-C10) in CCL39 cells and studied the effects of alpha 2-agonists on reinitiation of DNA synthesis in qui...

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Bibliographische Detailangaben
Hauptverfasser: Seuwen, K, Magnaldo, I, Kobilka, B K, Caron, M G, Regan, J W, Lefkowitz, R J, Pouysségur, J
Format: Artikel
Sprache:en
Veröffentlicht: 1990
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC361538/
https://ncbi.nlm.nih.gov/pubmed/1981685
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