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Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.
Substitution of asparagine for serine at position 17 decreased the affinity of rasH p21 for GTP 20- to 40-fold without significantly affecting its affinity for GDP. Transfection of NIH 3T3 cells with a mammalian expression vector containing the Asn-17 rasH gene and a Neor gene under the control of t...
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| Hoofdauteurs: | , |
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| Formaat: | Artikel |
| Taal: | en |
| Gepubliceerd in: |
1988
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC363555/ https://ncbi.nlm.nih.gov/pubmed/3145408 |
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