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Burkitt lymphoma cell line carrying a variant translocation creates new DNA at the breakpoint and violates the hierarchy of immunoglobulin gene rearrangement.

The Burkitt lymphoma cell line KK124, which contains a reciprocal t(8;22) translocation, was shown to have rearranged in a region 3' to the c-myc proto-oncogene on chromosome 8 and 5' to the lambda constant region on chromosome 22. The breakpoint was cloned and sequenced, revealing that c-...

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Bibliografski detalji
Glavni autori: Denny, C T, Hollis, G F, Magrath, I T, Kirsch, I R
Format: Članak
Jezik:en
Izdano: 1985
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC369135/
https://ncbi.nlm.nih.gov/pubmed/3018508
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