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Interleukin-7 supports survival of T-cell receptor-β-expressing CD4(−) CD8(−) double-negative thymocytes
Among the milestones that occur during T-cell development in the thymus is the expression of T-cell receptor-β (TCR-β) and the formation of the pre-TCR complex. Signals emanating from the pre-TCR trigger survival, proliferation and differentiation of T-cell precursors. Although the pre-TCR is essent...
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| Format: | Artigo |
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| Sprog: | en |
| Udgivet: |
Blackwell Science Inc
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3719948/ https://ncbi.nlm.nih.gov/pubmed/23215679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12050 |
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