Disposition of Caspofungin, a Novel Antifungal Agent, in Mice, Rats, Rabbits, and Monkeys

The metabolism, excretion, and pharmacokinetics of caspofungin (Cancidas; Merck & Co., Inc.) were investigated after administration of a single intravenous dose to mice, rats, rabbits, and monkeys. Caspofungin had a low plasma clearance (0.29 to 1.05 ml/min/kg) and a long terminal elimination ha...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sandhu, Punam, Xu, Xin, Bondiskey, Peter J., Balani, Suresh K., Morris, Michael L., Tang, Yui S., Miller, Alisha R., Pearson, Paul G.
Formatua: Artikulua
Hizkuntza:en
Argitaratua: American Society for Microbiology 2004
Gaiak:
Experimental Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC375331/
https://ncbi.nlm.nih.gov/pubmed/15047529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1272-1280.2004
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC375331/
https://ncbi.nlm.nih.gov/pubmed/15047529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.4.1272-1280.2004

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