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DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state.

Transgenic mice expressing the sequences coding for the envelope proteins of the hepatitis B virus (HBV) in the liver have been used as a model of the HBV chronic carrier state. We evaluated the possibility of inducing a specific immune response to the viral envelope antigens and thus potentially co...

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Autori principali: Mancini, M, Hadchouel, M, Davis, H L, Whalen, R G, Tiollais, P, Michel, M L
Natura: Articolo
Lingua:en
Pubblicazione: 1996
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC38020/
https://ncbi.nlm.nih.gov/pubmed/8901610
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