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Chromosomal double-strand break repair in Ku80-deficient cells.
The x-ray sensitive hamster cell line xrs-6 is deficient in DNA double-strand break (DSB) repair and exhibits impaired V(D)J recombination. The molecular defect in this line is in the 80-kDa subunit of the Ku autoantigen, a protein that binds to DNA ends and recruits the DNA-dependent protein kinase...
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| Autori principali: | , , , , |
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| Natura: | Articolo |
| Lingua: | en |
| Pubblicazione: |
1996
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC38571/ https://ncbi.nlm.nih.gov/pubmed/8799130 |
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