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Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone.

Follicle stimulating hormone (FSH) plays essential roles in the maintenance and development of oocytes and spermatozoa in normal reproductive physiology. FSH possesses two subunits, alpha and beta, the latter being responsible for FSH biological specificity. We have cloned and sequenced the cDNA enc...

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Main Authors: Esch, F S, Mason, A J, Cooksey, K, Mercado, M, Shimasaki, S
Formato: Artigo
Idioma:en
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC386555/
https://ncbi.nlm.nih.gov/pubmed/3092216
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spelling pubmed-3865552004-04-23 Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone. Esch, F S Mason, A J Cooksey, K Mercado, M Shimasaki, S Proc Natl Acad Sci U S A Research Article Follicle stimulating hormone (FSH) plays essential roles in the maintenance and development of oocytes and spermatozoa in normal reproductive physiology. FSH possesses two subunits, alpha and beta, the latter being responsible for FSH biological specificity. We have cloned and sequenced the cDNA encoding the FSH beta chain from a bovine anterior pituitary cDNA library. The mature molecule is 109 amino acids long and is preceded by a 20-amino acid putative signal peptide. RNA gel blot analysis of bovine pituitary RNA shows that the mRNA encoding beta chain of FSH is approximately 1.7 kilobases in length. 1986-09 /pmc/articles/PMC386555/ /pubmed/3092216 Text en
institution US National Library of Medicine
collection PubMed Central
language en
format Article
topic Research Article
spellingShingle Research Article
Esch, F S
Mason, A J
Cooksey, K
Mercado, M
Shimasaki, S
Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone.
description Follicle stimulating hormone (FSH) plays essential roles in the maintenance and development of oocytes and spermatozoa in normal reproductive physiology. FSH possesses two subunits, alpha and beta, the latter being responsible for FSH biological specificity. We have cloned and sequenced the cDNA encoding the FSH beta chain from a bovine anterior pituitary cDNA library. The mature molecule is 109 amino acids long and is preceded by a 20-amino acid putative signal peptide. RNA gel blot analysis of bovine pituitary RNA shows that the mRNA encoding beta chain of FSH is approximately 1.7 kilobases in length.
author Esch, F S
Mason, A J
Cooksey, K
Mercado, M
Shimasaki, S
author_facet Esch, F S
Mason, A J
Cooksey, K
Mercado, M
Shimasaki, S
author_sort Esch, F S
title Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone.
title_short Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone.
title_full Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone.
title_fullStr Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone.
title_full_unstemmed Cloning and DNA sequence analysis of the cDNA for the precursor of the beta chain of bovine follicle stimulating hormone.
title_sort cloning and dna sequence analysis of the cdna for the precursor of the beta chain of bovine follicle stimulating hormone.
publishDate 1986
url https://ncbi.nlm.nih.gov/pmc/articles/PMC386555/
https://ncbi.nlm.nih.gov/pubmed/3092216
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