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Tumor necrosis factor receptor 1-mediated signaling is required for skin cancer development induced by NF-κB inhibition

NF-κB signaling plays an important role in skin development and epidermal growth control. Moreover, inhibition of NF-κB signaling in murine epidermal keratinocytes in vivo, by expression of a keratin 5 (K5)-directed superrepressor form of inhibitor of NF-κB (IκBα), results in an inflammatory respons...

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Hlavní autoři: Lind, Maria H., Rozell, Björn, Wallin, Robert P. A., van Hogerlinden, Max, Ljunggren, Hans-Gustaf, Toftgård, Rune, Sur, Inderpreet
Médium: Článek
Jazyk:en
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC387358/
https://ncbi.nlm.nih.gov/pubmed/15044707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307106101
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