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Minireview: Dynamic Structures of Nuclear Hormone Receptors: New Promises and Challenges

Therapeutic targeting of nuclear receptors (NRs) is presently restricted due to 2 constraints: 1) a limited knowledge of the structural dynamics of intact receptor when complexed to DNA and coregulatory proteins; and 2) the inability to more selectively modulate NR actions at specific organ/gene tar...

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Bibliographic Details
Format: Article
Language:en
Published: Endocrine Society 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896641/
https://ncbi.nlm.nih.gov/pubmed/24284822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1334
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