TY  - JOUR
T1  - Evidence that a major class of mouse endogenous long terminal repeats (LTRs) resulted from recombination between exogenous retroviral LTRs and similar LTR-like elements (LTR-IS).
A1  - Schmidt, M
LA  - en
YR  - 1984
UL  - http://buscaintegrada.pucsp.br/vufind/Record/pubmed-391997
AB  - Two endogenous retroviral long terminal repeats (LTRs) were sequenced and compared to LTR-IS (a family of insertion-element-like sequences with structural features of solitary retroviral LTRs) and to Moloney murine leukemia virus DNA. The sequence comparisons revealed that the major difference between these two endogenous LTRs is a 190-base-pair segment which is also present in LTR-IS elements. Hybridization analysis of DNAs from several mouse species using specific probes shows linkage of the 190-base-pair segment to a LTR-IS specific fragment. It is concluded that the major class of endogenous LTRs has been generated by recombination between exogenous retroviral LTRs and LTR-IS sequences.
KW  - Research Article
ER  -