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Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.
The Shc adaptor protein contains two phosphotyrosine [Tyr(P)]binding modules--an N-terminal Tyr(P) binding (PTB) domain and a C-terminal Src homology 2 (SH2) domain. We have compared the ability of the Shc PTB domain to bind the receptors for nerve growth factor and insulin, both of which contain ju...
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| Autori principali: | , , , , , , , |
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| Natura: | Articolo |
| Lingua: | en |
| Pubblicazione: |
1996
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC40012/ https://ncbi.nlm.nih.gov/pubmed/8577769 |
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