Ag lódáil...
USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling
Protein kinase ALK3/BMPR1A mediates bone morphogenetic protein (BMP) signalling through phosphorylation and activation of SMADs 1/5/8. SMAD6, a transcriptional target of BMP, negatively regulates the BMP pathway by recruiting E3 ubiquitin ligases and targeting ALK3 for ubiquitin-mediated degradation...
Sábháilte in:
| Formáid: | Alt |
|---|---|
| Teanga: | en |
| Foilsithe / Cruthaithe: |
The Royal Society
2014
|
| Ábhair: | |
| Rochtain ar líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4042855/ https://ncbi.nlm.nih.gov/pubmed/24850914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.140065 |
| Clibeanna: |
Cuir clib leis
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
|
Bí ar an gcéad duine le trácht a dhéanamh!