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Crystal structure of the nucleotide-binding domain of mortalin, the mitochondrial Hsp70 chaperone

Mortalin, a member of the Hsp70-family of molecular chaperones, functions in a variety of processes including mitochondrial protein import and quality control, Fe-S cluster protein biogenesis, mitochondrial homeostasis, and regulation of p53. Mortalin is implicated in regulation of apoptosis, cell s...

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Podrobná bibliografie
Médium: Článek
Jazyk:en
Vydáno: Blackwell Publishing Ltd 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093958/
https://ncbi.nlm.nih.gov/pubmed/24687350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2466
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