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Characterization of the VHL tumor suppressor gene product: localization, complex formation, and the effect of natural inactivating mutations.
The human VHL tumor suppressor gene has been implicated in the inherited disorder von Hippel-Lindau disease and in sporadic renal carcinoma. The homologous rat gene encodes a 185-amino acid protein that is 88% sequence identical to the aligned 213-amino acid human VHL gene product. When expressed in...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Article |
| Langue: | en |
| Publié: |
1995
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC41537/ https://ncbi.nlm.nih.gov/pubmed/7604013 |
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