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Two nuclear localization signals present in the basic-helix 1 domains of MyoD promote its active nuclear translocation and can function independently.
MyoD, a member of the family of helix-loop-helix myogenic factors that plays a crucial role in skeletal muscle differentiation, is a nuclear phosphoprotein. Using microinjection of purified MyoD protein into rat fibroblasts, we show that the nuclear import of MyoD is a rapid and active process, bein...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Makale |
| Dil: | en |
| Baskı/Yayın Bilgisi: |
1995
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC42001/ https://ncbi.nlm.nih.gov/pubmed/7753857 |
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