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Structure-Guided Functional Characterization of Enediyne Self-Sacrifice Resistance Proteins, CalU16 and CalU19

[Image: see text] Calicheamicin γ(1)(I) (1) is an enediyne antitumor compound produced by Micromonospora echinospora spp. calichensis, and its biosynthetic gene cluster has been previously reported. Despite extensive analysis and biochemical study, several genes in the biosynthetic gene cluster of 1...

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Format: Artikel
Sprache:en
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201346/
https://ncbi.nlm.nih.gov/pubmed/25079510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500327m
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