Decrease in microviscosity and cholesterol content of rat liver plasma membranes after chronic ethanol feeding.

This investigation was performed to determine whether chronic ethanol feeding alters the lipid composition or the fluidity of liver plasma membranes. Male Sprague-Dawley rats were pair-fed nutritionally adequate liquid diets containing ethanol as 36% of energy or an isocaloric amount of carbohydrate...

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Main Authors: Yamada, S, Lieber, C S
Formato: Artigo
Idioma:en
Publicado em: 1984
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC425422/
https://ncbi.nlm.nih.gov/pubmed/6511927
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spelling pubmed-4254222004-07-07 Decrease in microviscosity and cholesterol content of rat liver plasma membranes after chronic ethanol feeding. Yamada, S Lieber, C S J Clin Invest Research Article This investigation was performed to determine whether chronic ethanol feeding alters the lipid composition or the fluidity of liver plasma membranes. Male Sprague-Dawley rats were pair-fed nutritionally adequate liquid diets containing ethanol as 36% of energy or an isocaloric amount of carbohydrate for 4-5 wk. Contrasting with other membranes, chronic ethanol feeding resulted in an increase in hepatic plasma membrane fluidity as assessed by fluorescence anisotropy. This alteration was associated with a decrease in plasma membrane cholesterol content. 1984-12 /pmc/articles/PMC425422/ /pubmed/6511927 Text en
institution US National Library of Medicine
collection PubMed Central
language en
format Article
topic Research Article
spellingShingle Research Article
Yamada, S
Lieber, C S
Decrease in microviscosity and cholesterol content of rat liver plasma membranes after chronic ethanol feeding.
description This investigation was performed to determine whether chronic ethanol feeding alters the lipid composition or the fluidity of liver plasma membranes. Male Sprague-Dawley rats were pair-fed nutritionally adequate liquid diets containing ethanol as 36% of energy or an isocaloric amount of carbohydrate for 4-5 wk. Contrasting with other membranes, chronic ethanol feeding resulted in an increase in hepatic plasma membrane fluidity as assessed by fluorescence anisotropy. This alteration was associated with a decrease in plasma membrane cholesterol content.
author Yamada, S
Lieber, C S
author_facet Yamada, S
Lieber, C S
author_sort Yamada, S
title Decrease in microviscosity and cholesterol content of rat liver plasma membranes after chronic ethanol feeding.
title_short Decrease in microviscosity and cholesterol content of rat liver plasma membranes after chronic ethanol feeding.
title_full Decrease in microviscosity and cholesterol content of rat liver plasma membranes after chronic ethanol feeding.
title_fullStr Decrease in microviscosity and cholesterol content of rat liver plasma membranes after chronic ethanol feeding.
title_full_unstemmed Decrease in microviscosity and cholesterol content of rat liver plasma membranes after chronic ethanol feeding.
title_sort decrease in microviscosity and cholesterol content of rat liver plasma membranes after chronic ethanol feeding.
publishDate 1984
url https://ncbi.nlm.nih.gov/pmc/articles/PMC425422/
https://ncbi.nlm.nih.gov/pubmed/6511927
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