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Endonuclease-induced, targeted homologous extrachromosomal recombination in Xenopus oocytes.
Homologous recombination in gene targeting in most organisms occurs by an inefficient mechanism. Inducing a double-strand break in the chromosomal target may increase this efficiency by allowing recombination to proceed by the highly efficient single-strand annealing mechanism. A gene targeting expe...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | en |
| Publicado: |
1995
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC42709/ https://ncbi.nlm.nih.gov/pubmed/7846056 |
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