Efficacy of Recombinant Human Interleukin 7 in a Patient With Severe Lymphopenia-Related Progressive Multifocal Leukoencephalopathy

In this study, we report the case of a patient with profound lymphopenia after allogenic bone marrow transplantation who developed severe progressive multifocal leukoencephalopathy. Single-agent recombinant human interleukin-7 therapy was associated with restoration of anti-John Cunningham polyomavi...

Descripció completa

Guardat en:
Dades bibliogràfiques
Format: Article
Idioma:en
Publicat: Oxford University Press 2014
Matèries:
Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281783/
https://ncbi.nlm.nih.gov/pubmed/25734144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofu074
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
id pubmed-4281783
record_format dspace
institution US National Library of Medicine
collection PubMed Central
language en
format Article
topic Brief Reports
spellingShingle Brief Reports
Efficacy of Recombinant Human Interleukin 7 in a Patient With Severe Lymphopenia-Related Progressive Multifocal Leukoencephalopathy
topic_facet Brief Reports
description In this study, we report the case of a patient with profound lymphopenia after allogenic bone marrow transplantation who developed severe progressive multifocal leukoencephalopathy. Single-agent recombinant human interleukin-7 therapy was associated with restoration of anti-John Cunningham polyomavirus (JCV) T-cell responses, JCV clearance from cerebrospinal fluid, and a dramatic clinical improvement.
author_sort Gasnault, Jacques
title Efficacy of Recombinant Human Interleukin 7 in a Patient With Severe Lymphopenia-Related Progressive Multifocal Leukoencephalopathy
title_short Efficacy of Recombinant Human Interleukin 7 in a Patient With Severe Lymphopenia-Related Progressive Multifocal Leukoencephalopathy
title_full Efficacy of Recombinant Human Interleukin 7 in a Patient With Severe Lymphopenia-Related Progressive Multifocal Leukoencephalopathy
title_fullStr Efficacy of Recombinant Human Interleukin 7 in a Patient With Severe Lymphopenia-Related Progressive Multifocal Leukoencephalopathy
title_full_unstemmed Efficacy of Recombinant Human Interleukin 7 in a Patient With Severe Lymphopenia-Related Progressive Multifocal Leukoencephalopathy
title_sort efficacy of recombinant human interleukin 7 in a patient with severe lymphopenia-related progressive multifocal leukoencephalopathy
publisher Oxford University Press
publisher_facet Oxford University Press
publishDate 2014
url https://ncbi.nlm.nih.gov/pmc/articles/PMC4281783/
https://ncbi.nlm.nih.gov/pubmed/25734144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofu074
_version_ 1872505876836777984

Ítems similars