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Genetic analysis of the cell surface: association of human chromosome 5 with sensitivity to diphtheria toxin in mouse-human somatic cell hybrids.

Diphtheria toxin inhibits protein synthesis in eukaryotic cells by catalyzing inactivation of elongation factor 2. The 10,000-fold greater sensitivity in vitro to diphtheria toxin of human cells as compared to mouse cells seems to be attributable to a difference at the level of the cell membrane. Mo...

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Bibliografski detalji
Glavni autori: Creagan, R P, Chen, S, Ruddle, F H
Format: Članak
Jezik:en
Izdano: 1975
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC432732/
https://ncbi.nlm.nih.gov/pubmed/1056028
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