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Intracellular calcium dependence of gene expression in single T lymphocytes.

In T lymphocytes, intracellular Ca2+ concentration ([Ca2+]i) rises within seconds of T-cell antigen-receptor stimulation and initiates the synthesis and secretion of interleukin 2, a cytokine essential for T-cell proliferation and the immune response. Using video-imaging techniques, we tracked [Ca2+...

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Main Authors: Negulescu, P A, Shastri, N, Cahalan, M D
格式: Artigo
語言:en
出版: 1994
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC43473/
https://ncbi.nlm.nih.gov/pubmed/8146203
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