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Human pDCs preferentially sense enveloped hepatitis A virions

Unlike other picornaviruses, hepatitis A virus (HAV) is cloaked in host membranes when released from cells, providing protection from neutralizing antibodies and facilitating spread in the liver. Acute HAV infection is typified by minimal type I IFN responses; therefore, we questioned whether plasma...

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Format: Artikel
Sprache:en
Veröffentlicht: American Society for Clinical Investigation 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382264/
https://ncbi.nlm.nih.gov/pubmed/25415438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI77527
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