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Hsp70 clears misfolded kinases that partitioned into distinct quality-control compartments

Hsp70 aids in protein folding and directs misfolded proteins to the cellular degradation machinery. We describe discrete roles of Hsp70,SSA1 as an important quality-control machinery that switches functions to ameliorate the cellular environment. SSA1 facilitates folding/maturation of newly synthesi...

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Médium: Článek
Jazyk:en
Vydáno: The American Society for Cell Biology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4436772/
https://ncbi.nlm.nih.gov/pubmed/25739454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E14-08-1262
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