Antisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo.

To examine the role of acetylcholinesterase (EC 3.1.1.7) in hematopoietic cell proliferation and differentiation, we administered a 15-mer phosphorothioate oligonucleotide, antisense to the corresponding ACHE gene (AS-ACHE), to primary mouse bone marrow cultures. Within 2 hr of AS-ACHE addition to t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Soreq, H, Patinkin, D, Lev-Lehman, E, Grifman, M, Ginzberg, D, Eckstein, F, Zakut, H
Formatua: Artikulua
Hizkuntza:en
Argitaratua: 1994
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC44513/
https://ncbi.nlm.nih.gov/pubmed/8058733
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Internet

https://ncbi.nlm.nih.gov/pmc/articles/PMC44513/
https://ncbi.nlm.nih.gov/pubmed/8058733

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